Much evidence has emerged in the health sciences over the past few decades of psychosocial and emotional factors being implicated in the aetiology, prognosis and clinical management of health conditions. Building upon the foundational work of Dr. Ryke Geerd Hamer, Dr Claude Sabbah’s lifelong research, and the proposed biopsychosocial model of Dr. George Engel, this ensemble of papers presents a novel perspective on the aetiology of illness (including cancer), which offers a comprehensive model that bridges the gap between mind and body. While the task is focussed on the health sciences, it is set within the wider context of cross disciplinary theory, research and problem-solving in contemporary life and human sciences.

Drawing upon Hamer's concept of the "German New Medicine" and Sabbah’s “Total Biology”, both based on the science of embryology and the evolutionary history/biology of man for survival, our framework is the recognition of illness as a “bio-logical” coping response to unresolved inner conflicts (stressors), rejecting the idea of illnesses as random meaningless errors of Nature’s extraordinarily orchestrated machine, or immune system failure. It integrates Engel's acknowledgement of the interconnectedness of biological, psychological, and social factors in health and disease.

The neuro-psyche-somatic model emphasizes the dynamic interactions between the brain, the psyche and the body in the manifestation of inner conflicts that contribute to disease states. Dr Hamer (and Dr Sabbah) delineates the mechanisms through which chronic stress, emotional dysregulation, and unresolved trauma contribute to the initiation and progression of diseases. Within this paradigm, illness is viewed as a dynamic process characterized by two distinct phases: an active phase, marked by heightened sympathetic activity and physiological adaptations aimed at coping with perceived threats, and a subsequent healing phase, characterized by parasympathetic dominance and restoration of homeostasis. By presenting Hamer's discoveries and Engel's model, I aim to provide a novel comprehensive understanding of illness genesis. This integrative perspective holds promise for advancing both theoretical understanding and clinical practice in the field of integrative medicine, not to mention the economical impact on the health system.

It's important to note that I coined the term "neuro-psyche-somatic": first to encapsulate the integrated concept of neurological, emotional, and corporeal factors in health and illness, and second to dissociate myself from Dr Hamer’s harsh, sometimes antagonizing criticism of the existing biomedical model, and drastic position against modern medicine’s practices.

Despite two decades of clinical observations yielding results consistent with Dr. Hamer's and Dr Sabbah’s fundamental work, there remains a notable gap in scientific research corroborating these findings. This shortage of empirical evidence underscores the need for further investigation to elucidate the underlying mechanisms and validate the efficacy of the neuro-emo-somatic model. As an advocate for this evolving paradigm, I am dedicated to contributing to its progress through rigorous scientific inquiry to substantiate its clinical significance and therapeutic potential.

Motivated by the overwhelming absence of comprehension of the origins of diseases and the pervasive distressing sense of being cursed that many individuals experience when confronted with illness, I propose there is a bio-logical meaning to illnesses that could revolutionize both our perception of them and their relevance to our lives. By elucidating the intricate interplay between emotional states and physiological responses, I aim to empower individuals with a renewed sense of agency and hope in healing, not only physically and psychologically, but also spiritually.

By leveraging interdisciplinary collaborations and methodological innovations, I seek to address this knowledge gap and pave the way for the integration of neuro-psyche-somatic principles into mainstream healthcare practices. We propose that establishing therapeutic interventions aiming at resolving underlying inner conflicts and restoring emotional equilibrium, would facilitate the transition from the active to the healing phase of illness. This understanding of disease pathogenesis has profound implications for personalized medicine, psycho-oncology, and the development of integrative approaches to healthcare delivery. Through our collaborative efforts, and driven by the conviction that healing is attainable on multiple levels, I endeavor to catalyze a paradigm shift in medicine towards a more “wholestic” and patient-centered approach, grounded in scientific rigor and compassionate care.